cytogenetics

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Related to Cytogenetic analysis: cytogeneticist, Cytogenetic map, Chromosome analysis

cytogenetics

 [si″to-jĕ-net´iks]
that branch of genetics devoted to the cellular constituents concerned in heredity, i.e., the chromosomes.
clinical cytogenetics the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks),
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes.

Cytogenetics arose as a fusion of 19th-century cytology and 20th-century genetics, which came into being in 1903 with the articulation of the chromosome theory of inheritance. The developing field concerned itself with detailing the behavior of chromosomes and their functional subunits, the genes, during reproduction, and with relating that behavior statistically to characteristics of the resulting cells or animals. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been fixed in mitosis and stained with various agents to delineate characteristic bands. DNA probes can be applied to locate specific gene sequences. Karyotyping is the arrangement of photographs of stained chromosomes in a standard format. Cytogenetic techniques are used to test for inborn errors of metabolism and genomic aberrations such as Down syndrome and to determine sex in cases where anatomy is inconclusive.

cytogenetics

/cy·to·ge·net·ics/ (-jĕ-net´iks) the branch of genetics devoted to cellular constituents concerned in heredity, i.e. chromosomes.
clinical cytogenetics  the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.

cytogenetics

(sī′tō-jə-nĕt′ĭks)
n. (used with a sing. verb)
The branch of genetics that deals with the cellular components, particularly chromosomes, that are associated with heredity.

cy′to·ge·net′ic, cy′to·ge·net′i·cal adj.
cy′to·ge·net′i·cal·ly adv.
cy′to·ge·net′i·cist (-sĭst) n.

cytogenetics

[sī′tōjənet′iks]
the branch of genetics that studies the cellular constituents concerned with heredity, primarily the structure, function, and origin of the chromosomes. One kind of cytogenetics is clinical cytogenetics. Also called cytogenics.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks)
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been arranged as karyotypes. Individuals can be classified according to characteristic banding patterns that appear when the karyotypes are exposed to some dyes. In addition, DNA probes may be applied to locate specific gene sequences. Cytogenetic techniques are used to test for inborn errors of metabolism, for disorders such as Down syndrome, and to determine sex in cases where anatomy is inconclusive.

cytogenetics

the study of the inheritance of cells and their chromosomes. Cytogenetic analysis of foetal cells (see AMNIOCENTESIS and CYSTIC FIBROSIS) is used to assess potential risks to the baby.

cytogenetics

that branch of genetics devoted to the cellular constituents concerned in heredity, i.e. the chromosomes; the combined sciences of genetics and cytology.

clinical cytogenetics
the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathological conditions.
References in periodicals archive ?
Cytogenetic analysis using Prenatal BoBsTM gave a conclusive result for 62 of the 70 samples (88.
Thus, the precise diagnosis and evaluation of patients with sex chromosome abnormality with conventional cytogenetic analysis is essential for the evaluation of phenotype and karyotype correlations, followed by genetic counseling.
For cytogenetic analysis the part of sample was fixed in cytogenetic transport medium.
Regarding the cytogenetic analysis, in 5 of the 34 analyzed specimens, chromosomal preparations could not be obtained, or the quality from the obtained ones was not suitable for analysis.
17) Cytogenetic analysis of the tumor and bone marrow may aid in the confirmation of a presumptive diagnosis whenimmunohistochemical studies produce conflicting results or when bone marrow involvement in leukemia lags behind peripheral manifestations.
Laboratory techniques and applications for researchers investigating the identification and function of genes relevant to normal physiology and cancer are described by specialists in specific aspects of gene identification and full-length gene cloning, gene profiling, the chromatin modification of gene regulation, bacterial artificial chromosomes, cancer cytogenetic analysis, and other topics.
It may someday take the place of our standard techniques for cytogenetic analysis, but for now, it is a valuable addition to the available diagnostic tests.
Cytogenetic analysis using quantitative, high sensitivity, fluorescence hybridization.
Additionally, cytogenetic analysis may have some difficulties when compared with other kinds of analysis: the specimens must be kept alive until the slide preparations, some of them do not have cell division at the moment of analysis, and some techniques are expensive.
The proportion of cases with a known chromosomal abnormality based on cytogenetic analysis was determined, and the types of chromosomal abnormalities were described.
As part of the agreement, Avalon will provide Aventis with a subset of its library of more than 200 identified amplicons (regions of chromosomal amplification) that have been discovered through cytogenetic analysis.