methemoglobin reductase

(redirected from Cytochrome-b5 reductase)
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met·he·mo·glo·bin re·duc·tase

a flavoenzyme catalyzing the reduction of methemoglobin to hemoglobin in the red blood cell.

methemoglobin reductase

An enzyme found in significant amounts in erythrocytes that catalyzes the reduction of methemoglobin in conjunction with the coenzyme nicotine adenine dinucleotide phosphate and other enzymes.
See also: methemoglobin
References in periodicals archive ?
2-) Nussenzveig RH, Lingam HB, Gaikwad A, Zhu Q, Jing N, Prchal JT (2006): A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia.
the NADH-dependent cytochrome-b5 reductase pathway (active under physiological conditions)
In pathological states of methaemoglobinaemia, this extra methaemoglobin-reducing pathway acts synergistically with the inherently active cytochrome-b5 reductase pathway to allow faster reduction of methaemoglobin.