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cytochrome P-450
(redirected from Cytochrome P450)

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cytochrome P-450
Etymology: Gk, kytos, cell, chroma, color
a protein involved with extramitochondrial electron transport in the liver and during drug detoxification.
cytochrome P-450
Clinical pharmacology A superfamily of heme-containing enzymes–CYPs of the electron transport chain, which have multiple activities, including activation of molecular O2 for incorporation into unactivated hydrocarbons, xenobiotic metabolism, bioremediation, and breakdown of drugs and toxins
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CORINA is used within StarDrop's predictive P450 metabolism models which identify metabolic liabilities of candidate molecules against the major cytochrome P450 enzymes.
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The researchers discovered two cytochrome P450 genes in A.
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Many drug interactions are caused by cytochrome P450 activity or inhibition.
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