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Cytochrome P-450 enzymes

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Cytochrome P-450 enzymes (sīˑ·t·krōmˈ pēˑ-fōrˈ fifˈ·tē enˑ·zīmz),
n.pl oxygenating catalysts responsible for the reactions used by the body, especially the liver, to detoxify drugs and other substances.


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Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes.
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians.
The inhibition of the cytochrome P-450 enzymes by ranitidine or cimetidine can also lead to potentially dangerous side effects with certain other psychiatric medications.
 
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