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ALPHABETArterial Pulmonary Hypertension & Beraprost European Study. A clinical trial assessing the effects of a prostacyclin analogue, beraprost, in patients with pulmonary arterial hypertension (PAH) and NYHA II & III disease
Conclusion Beraprost increases the 6-minute walk distance in patients with PAH and results in an improved Borg dyspnoea index.
Note A later US study saw early benefits in class II or III patients which attenuate with time.