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ciclosporin
(redirected from Cyclosporins)

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ciclosporin.
ciclosporin (cyclosporine) 
An immunosuppressant used in the treatment of the ocular manifestation of autoimmune diseases, uveitis, scleritis, keratoconjunctivitis sicca, ligneous conjunctivitis, and to prevent rejection of corneal grafts, etc. It is believed to exert its immunosuppressive effect by inhibiting the activation of cytotoxic T-lymphocytes. See immunosuppressants.


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Thus, 10 cyclophilins wind up facing outward, with 10 cyclosporins sandwiched between them.
Cyclosporins protect damaged neurons from dying, and have been shown to be potent neuroprotectants in models of acute brain attack including stroke, traumatic brain and spinal cord injury, and also the chronic neurodegenerative diseases of Alzheimer's, Parkinson's, Huntington's and ALS.
Cyclosporins protect the brain mitochondria and prevent neuron death in neurological disease.
 
 
 
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