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ciclosporin |
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ciclosporin. See cyclosporin. ciclosporin (cyclosporine) An immunosuppressant used in the treatment of the ocular manifestation of autoimmune diseases, uveitis, scleritis, keratoconjunctivitis sicca, ligneous conjunctivitis, and to prevent rejection of corneal grafts, etc. It is believed to exert its immunosuppressive effect by inhibiting the activation of cytotoxic T-lymphocytes. See immunosuppressants. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Eckstein's presentation will discuss Enanta's most recent cyclosporine research that includes the development of new cyclosporine analogs, EP-314 and EP-012637, which, when converted into non-toxic metabolites, prove to be distinct from Cyclosporine A and its metabolites that have limited therapeutic potential due to kidney toxicity. He continued, "Subject to providing satisfactory responses to all questions the FDA may have, we look forward to receiving US market clearance for CYCLOSPORINE as a bioequivalent product to Neoral and launch. |
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