cycloSERINE

cycloserine /cy·clo·ser·ine/ (-sĕ´rēn) an antibiotic produced by Streptomyces orchidaceus or obtained synthetically; used as a tuberculostatic and in treatment of urinary tract infections.

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cycloSERINE

[sī′klōser′ēn]

an antibiotic.

indications It is prescribed in the treatment of active pulmonary and extrapulmonary tuberculosis.

contraindications Epilepsy, depression, severe anxiety, psychosis, severe renal insufficiency, excessive concurrent use of alcohol, or known hypersensitivity to this drug prohibits its use.

adverse effects Among the most serious reactions are central nervous system toxic effects, including tremor, drowsiness, convulsions, and psychotic changes. Pyridoxine may be given concurrently to prevent these effects. Other side effects include arrhythmias and optic neuritis.

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cycloserine (sī´klōserēn),

n brand name: Seromycin Pulvules;
drug class: antitubercular;
action: inhibits cell wall synthesis, analog of D-alanine;
uses: pulmonary tuberculosis.

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cycloserine

Infectious disease A broad-spectrum antibiotic used for UTIs and TB Adverse effects CNS Sx, allergy, skin rash, ↑ LFTs