cyclooxygenase

(redirected from Cyclooxygenase inhibitors)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Cyclooxygenase inhibitors: Reye's syndrome, NSAIDs, Cyclooxygenase 2 inhibitors

cyclooxygenase

 [si″klo-ok´sĭ-jĕ-nās]
an activity of the enzyme prostaglandin endoperoxide synthase.

pros·ta·glan·din en·do·per·ox·ide syn·thase

a protein complex that catalyzes two steps in prostaglandin biosynthesis; the cyclooxygenase activity (which is inhibited by aspirin and indomethacin) converts arachidonate and 2O2 to prostaglandin G2; the hydroperoxidase activity uses glutathione to convert prostaglandin G2 to prostaglandin H2.
Synonym(s): cyclooxygenase

cyclooxygenase

/cy·clo·oxy·gen·ase/ (-ok´sĭ-jen-ās) a component of prostaglandin synthase (q.v.).

cyclooxygenase

(sī′klō-ŏk′sĭ-jə-nās′, -nāz′)
n.
1. See COX-1.
2. See COX-2.

cyclooxygenase

[si′klō·ok′səjĕnās]
an activity of the enzyme prostaglandin endoperoxide synthase.

Cyclooxygenase

An enzyme, found in most tissues, that helps turn some fatty acids into protaglandins.
Mentioned in: Cox-2 Inhibitors
References in periodicals archive ?
Neither a muscarinic receptor antagonist nor a cyclooxygenase inhibitor altered the Ch1LW-induced relaxation.
A cyclooxygenase inhibitor had no effect on the endothelium-dependent relaxation induced by Ch1LW, suggesting that muscarinic receptor stimulation, e.
Pharmacodynamic of cyclooxygenase inhibitors in humans.
Lin CN, Lee TH, Hsu MF, Wang JP, Ko FN, Teng CM (1997) 2', 5'- Dihydroxychalcone as a potent chemical mediator and cyclooxygenase inhibitor.
The idea is that indomethacin and other nonselective cyclooxygenase inhibitors are effective at stopping preterm labor, but they also cause substantial adverse effects such as oligohydramnios and constriction of the ductus arteriosus.
The OA market is estimated to be $6 billion for both non-steroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase inhibitors (Cox-2).

Full browser ?