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cycloheximide

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cycloheximide
an antibiotic produced by Streptomyces griseus that inhibits protein synthesis. It is too toxic and nonselective for common clinical use, but is used in treatment of cancers and management of graft-versus-host reactions following transplantation. Also used agriculturally for the control of fungal diseases of plants and turf and as a bacterial inhibitor in selective media for culturing fungi.


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The most common media for the isolation of dermatophytes are Dermatophyte Test Medium (DTM) and Sabouraud glucose agar (SDA) or potato-flakes agar, supplemented with chloramphenicol and cycloheximide to inhibit bacterial and saprophytic fungal growth.
Therefore, most bacteria grown on FMA should have been able to digest keratin and were therefore, considered keratin degrading, Both media contained 100 [mu]g/ml of cycloheximide to inhibit fungal growth (Smit et al.
In developing the medium, researchers used cycloheximide and cefoperazone.
 
 
 
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