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COX-2 inhibitor
(redirected from Cyclo-oxygenase-2 inhibitor)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
COX-2 inhibitor (kkst)
n.
Any of a class of nonsteroidal anti-inflammatory drugs that cause fewer gastrointestinal side effects by selective inhibition of prostaglandin formation.

COX-2 inhibitor
Cyclooxygenase-2 inhibitor Pain management A class of analgesics with fewer side effects than those of conventional NSAIDs–which inhibit both cyclooxygenases–COX-1 and COX-2; COX-1 protects the gastric mucosa, preventing ulcers, bleeding, and other digestive tract problems. See COX-2, Prostaglandin.


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Combination of a cyclo-oxygenase-2 inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a randomised double-blind trial.
Relationship Between Selective Cyclooxygenase-2 Inhibitors and Acute Myocardial Infarction in Older Adults, 109 Circulation 2068, 2068-73 (2004); Julia Hippisley-Cox & Carol Coupland, Risk of Myocardial Infarction in Patients Taking Cyclo-Oxygenase-2 Inhibitors or Conventional Nonsteroidal Anti-Inflammatory Drugs: Population Based Nested Case-Control Analysis, 330 Brit.
 
 
 
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