CYCS

(redirected from Cyc)
Also found in: Acronyms, Encyclopedia, Wikipedia.

CYCS

A gene on chromosome 7p15.3 that encodes cytochrome c, an electron carrier protein, which transfers electrons from the heme group of the cytochrome c1 subunit of cytochrome reductase to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. CYCS plays a role in apoptosis by suppressing anti-apoptotic members or by activating pro-apoptotic members of the Bcl-2 family, leading to altered mitochondrial membrane permeability and the release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 activates caspase-9, which then accelerates apoptosis by activating other caspases.

Molecular pathology
Defects in CYCS cause thrombocytopaenia type 4.
References in periodicals archive ?
In case of large common-sense ontologies, such as Cyc Knowledge Base, the user entering new knowledge very often needs a particular ontology subset of his domain interest.
3) The Wegener's Granulomatosis Etanercept Trial (WGET) (4) examined whether the addition of etanercep would have an effect on maintaining remission in WG patients treated with CYC (severe disease) or MTX (limited disease) to induce an initial remission.
The CITs at CYC for this year are Polly Fung, David Lin, Anna Liu, and Jeffrey Ng.
CYC tinkered with that original program and "Coaching to Make a Positive Difference" was born.
The CYC will present their findings to the school board, city council and mayor this November.
In one recent demonstration, an engineer asked Cyc about anthrax.
Best remains cautious about the further impact the European debt crisis could have on Atradius' operations, in particular in Spain through CyC, which represented about one-third of Atradius' total business in 2011.
These LEDs have a beam angle of 25 deg and can produce color washes around the center pencil-beam of light creating a double effect when used as an image projection fixture against a wall, cyc or other surface.
He was a talented full-back with Lockwood CYC OB in the Huddersfield District League and also an accomplished cricketer with Lockwood CYC in the Association League.
Today, CYC offers services to children and youth ages 3 - 19 in seven neighborhoods (Bridgeport, Grand Boulevard/Bronzeville, Humboldt Park, North Lawndale, South Shore, Riverdale/Altgeld and Roseland) through eight community centers and at CYC-Camp Rosenthal in Dowagiac, Michigan.
Kassira enjoys playing sports, video games, hanging out with friends and playing CYC basketball in his spare time.