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cyanogen bromide

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cyanogen bromide
reagent used to fragment peptide chains, since it cleaves only those peptide bonds in which methionine contributes the carbonyl group. Also used as coupling agent in affinity chromatography where it reacts with the Sepharose matrix forming a reactive product to which proteins, nucleic acids or other biopolymers can be coupled.


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With his microcapsules, he is working to combine four of these steps into one, while eliminating the need for the hazardous reagent, cyanogen bromide.
Cyanogen bromide is a reagent commonly used in protein sequencing because it specifically cleaves at the C-terminal side of methionine residues.
 
 
 
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