point of no return

(redirected from Crossing the Rubicon)
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point of no return

A colloquial term for a critical biochemical event that indicates lethal, irreversible changes in cells following ischemic cell injury.
See also: point
References in periodicals archive ?
She has also appeared in the films Crossing the Rubicon and The Unicylist and her TV credits include EastEnders, and playing barmaid Karen Ellis in the Five soap Family Affairs.
As the story goes, crossing the Rubicon was not the end of the line for Julius Caesar.
Crossing the Rubicon has become an idiom to mean passing the point of no return, from the crossing of the Rubicon River by Julius Caesar in 49 B.