CTSC

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CTSC

A gene on chromosome 11q14.2 that encodes cathepsin C, a ubiquitous lysosomal cysteine proteinase that co-ordinates activation of various serine proteinases (e.g., elastase, cathepsin G and granzymes A and B); it also activates neuraminidase and factor XIII. CTSC is highly expressed in the lungs, kidneys and placenta.

Molecular pathology
Defects in CTSC cause Papillon-Lefèvre syndrome, Haim-Munk syndrome and aggressive periodontititis type 1.
References in periodicals archive ?
These funds aim to preserve capital at maturity of the fund while providing exposure to equity market or other assets, based on CPPI methodology, which is formula-based investment criteria.
Table 1 illustrates the complex structure imposed by varied configurations of California medical care organizations and the nature of the CPPI demonstration project.
The RCA CPPI suite was developed to complement the national indices published with Moody's and uses the same methodology.
The main objective of this paper is to present and to analyze various CPPI type methods based on conditional floors and within a rather general parametric model.
CPPIs can be a useful addition to a bigger portfolio but you must take detailed advice from an independent financial adviser before you go ahead.
The CPPI gives companies payroll repayments of 13 percent for each qualifying job during the first 10 years of operations.
It said that the CPPI method maximizes exposure to equities in a bullish market to benefit from the gain, while in a bearish market it allocates a larger portion of the funds in money market instruments thus protecting the principal investment.
The CPPI, which is compiled in association with the Massachusetts Institute of Technology, is based on a repeat-sales regression (RSR) model, with conventional modifications and enhancements that are widely used in the real estate indices estimated in the academic community.
Usually, results about CPPI method are established under the assumption of continuous-time rebalancing.
Moody's produces its data using an index, called the Moody's/REAL CPPI, that tracks fluctuations in value by measuring the sale price of specific properties that have been sold at different points in the real estate cycle.
Additionally, CPPI expresses concern in the letter about domestic ethanol supplies, the province's planned enforcement of the mandate and the safety of ethanol-blended fuel use in certain vehicles.