| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 1,761,051,737 visitors served. |
|
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
COX-2 inhibitor |
Also found in: Encyclopedia, Wikipedia | 0.02 sec. |
COX-2 inhibitor Cyclooxygenase-2 inhibitor Pain management A class of analgesics with fewer side effects than those of conventional NSAIDs–which inhibit both cyclooxygenases–COX-1 and COX-2; COX-1 protects the gastric mucosa,
preventing ulcers, bleeding, and other digestive tract problems. See COX-2, Prostaglandin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
|
| ? Mentioned in | ? References in periodicals archive | |
|---|---|---|
Though this coxib-specific "prothrombotic mechanism" is still being investigated, the theory goes that by inhibiting the COX-2 enzymes that dilate blood vessels, while allowing the production of the COX-1 enzymes that cause blood platelets to stick, coxibs can create a friendly environment for the formation of dangerous blood clots in some people. In fact, while other agents have been shown to raise blood pressure between 4 and 6% in hypertensives, one coxib in particular appears to raise it by some 25 to 30%. Also included in other promoted medicines were global sales of Merck's coxib, ARCOXIA, which reached $57 million in the first quarter, compared with $30 million in the first quarter of 2004. |
| Medical Dictionary |
| Free Tools: |
For surfers:
Free toolbar & extensions |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|---|