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COX-2 inhibitor
(redirected from Cox-2 selectivity)

    Also found in: Encyclopedia, Wikipedia 0.01 sec.
COX-2 inhibitor (kkst)
n.
Any of a class of nonsteroidal anti-inflammatory drugs that cause fewer gastrointestinal side effects by selective inhibition of prostaglandin formation.
COX-2 inhibitor
Cyclooxygenase-2 inhibitor Pain management A class of analgesics with fewer side effects than those of conventional NSAIDs–which inhibit both cyclooxygenases–COX-1 and COX-2; COX-1 protects the gastric mucosa, preventing ulcers, bleeding, and other digestive tract problems. See COX-2, Prostaglandin.


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The report also evaluates Novartis' Prexige which is of particular interest since its structure is novel and also because it offers the greatest COX-2 selectivity of all COX-2 inhibitors that have entered advanced stages of development.
Research And Markets: Despite The Withdrawal Of Vioxx - Rofecoxib - ... by Business Wire
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