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COX-2 inhibitor

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
COX-2 inhibitor (kkst)
n.
Any of a class of nonsteroidal anti-inflammatory drugs that cause fewer gastrointestinal side effects by selective inhibition of prostaglandin formation.
COX-2 inhibitor
Cyclooxygenase-2 inhibitor Pain management A class of analgesics with fewer side effects than those of conventional NSAIDs–which inhibit both cyclooxygenases–COX-1 and COX-2; COX-1 protects the gastric mucosa, preventing ulcers, bleeding, and other digestive tract problems. See COX-2, Prostaglandin.


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? Mentioned in ? References in periodicals archive
 
Two nearly identical trials began in 1999 and 2001 but were stopped in 2004 when more than the expected number of participants developed heart problems while taking the drug, a COX-2 inhibitor.
Polyp stopper: controversial drug may prevent colon growths by Seppa, N. / Science News
From our perspective, it's that the FDA said Cox-2 inhibitors are associated with an increased risk of cardiovascular events.
Judge lets Vioxx lawyers discuss FDA memo by Curran, John / Los Angeles Business Journal
Don't write off the entire COX-2 inhibitor class of drugs, says Dr.
COX-2 inhibitors: what you need to know by National Women's Health Report
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