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modulation
(redirected from Covalent modulation)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
modulation /mod·u·la·tion/ (mod″u-la´shun)
1. the act of tempering.
2. the normal capacity of cell adaptability to its environment.
3. embryologic induction in a specific region.

antigenic modulation  the alteration of antigenic determinants in a living cell surface membrane following interaction with antibody.
biochemical modulation  in combination chemotherapy, the use of a substance to modulate the negative side effects of the primary agent, increasing its effectiveness or allowing a higher dose to be used.

mod·u·la·tion (mj-lshn)
n.
1. The functional and morphological fluctuation of cells in response to changing environmental conditions.
2. The variation of a property in an electromagnetic wave or signal, such as amplitude, frequency, or phase.

modulation
[mod′yəlā′shən]
an alteration in the magnitude or any variation in the duration of an electrical current. Modulation, which affects physiologic responses to various waveforms, may be continuous, interrupted, pulsed, or surging.

modulation
the capacity to regulate; widely used in biology, e.g. modulation of immune responses, food intake, etc.

antigenic modulation
the alteration of antigenic determinants in a living cell surface membrane following interaction with an antibody.
covalent modulation
activation or inactivation of enzymes, either by phosphorylation/dephosphorylation or by proteolytic cleavage. A major means of regulation of enzyme action by hormones.


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