modulation

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Related to Covalent modulation: covalent modification, Covalent bonding, Metabolic pathways

modulation

 [mod″u-la´shun]
the normal capacity of cell adaptability to its environment.
antigenic modulation the alteration of antigenic determinants in a living cell surface membrane following interaction with antibody.

mod·u·la·tion

(mod'yū-lā'shŭn),
1. The functional and morphologic fluctuation of cells in response to changing environmental conditions.
2. Systematic variation in a characteristic (for example, frequency, amplitude) of a sustained oscillation to code additional information.
3. A change in the kinetics of an enzyme or metabolic pathway.
4. The regulation of the rate of translation of mRNA by a modulating codon.
[L. modulor, to measure off properly]

modulation

/mod·u·la·tion/ (mod″u-la´shun)
1. the act of tempering.
2. the normal capacity of cell adaptability to its environment.
3. embryologic induction in a specific region.

antigenic modulation  the alteration of antigenic determinants in a living cell surface membrane following interaction with antibody.
biochemical modulation  in combination chemotherapy, the use of a substance to modulate the negative side effects of the primary agent, increasing its effectiveness or allowing a higher dose to be used.

modulation

[mod′yəlā′shən]
an alteration in the magnitude or any variation in the duration of an electrical current. Modulation, which affects physiological responses to various waveforms, may be continuous, interrupted, pulsed, or surging.

modulation

The regulation of the rate at which a specific gene is transcribed.

mod·u·la·tion

(mod'yŭ-lā'shŭn)
1. The functional and morphologic fluctuation of cells in response to changing environmental conditions.
2. Systematic variation in a characteristic (e.g., frequency, amplitude) of a sustained oscillation to code additional information.
3. A change in the kinetics of an enzyme or metabolic pathway.
4. The regulation of the rate of translation of mRNA by a modulating codon.
5. Change in parameters of electrotherapy (e.g., frequency, amplitude).
[L. modulor, to measure off properly]

modulation

the capacity to regulate; widely used in biology, e.g. modulation of immune responses, food intake, etc.

antigenic modulation
the alteration of antigenic determinants in a living cell surface membrane following interaction with an antibody.
covalent modulation
activation or inactivation of enzymes, either by phosphorylation/dephosphorylation or by proteolytic cleavage. A major means of regulation of enzyme action by hormones.