coumarin

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Related to Coumarins: Tannins, Flavonoids

coumarin

 [koo´mah-rin]
1. a principle extracted from the tonka bean, from which several anticoagulants are derived that inhibit hepatic synthesis of vitamin K–dependent coagulation factors.
2. any of these derivatives.

cou·ma·rin

(kū'mă-rin),
1. A general descriptive term applied to anticoagulants and other drugs derived from dicumarol, a component of the Tonka bean.
2. A fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and made synthetically from salicylic aldehyde; it is used to disguise unpleasant odors.
[coumarou, native name of Tonka bean]

coumarin

/cou·ma·rin/ (koo´mah-rin)
1. a principle extracted from the tonka bean; it contains a factor, dicumarol, that inhibits hepatic synthesis of vitamin K–dependent coagulation factors, and a number of its derivatives are used as anticoagulants in treating disorders characterized by excessive clotting.
2. any of these derivatives or any synthetic compound with similar activity.

coumarin

(ko͞o′mər-ĭn)
n.
A fragrant crystalline compound, C9H6O2, present in tonka beans and produced synthetically for use as a fragrance. Coumarin has been banned as a food additive in the United States because it can be toxic in large amounts.

cou′ma·ric (-mər-ĭk) adj.

coumarin

[ko̅o̅′mərin]
a class of orally active anticoagulant agents with warfarin as its prototype.
indications It is prescribed for prophylaxis and treatment of thrombosis and embolism.
contraindications Known hypersensitivity to the drug prohibits its use. It is not prescribed to patients who are at risk for hemorrhage or who are pregnant.
adverse effects The most serious adverse reaction is hemorrhage. Many other drugs interact with this drug to increase or decrease its effect.

cou·ma·rin

(kū'mă-rin)
Fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and also made synthetically from salicylic aldehyde; used to disguise unpleasant odors.

coumarin,

n C9H6O, derived from a variety of sources, including tonka bean and sweet clover; may also be artificially manufactured.
Enlarge picture
Coumarin.

cou·ma·rin

(kū'mă-rin)
A general descriptive term applied to anticoagulants and other drugs derived from dicumarol.

coumarin

1. a principle extracted from the tonka bean, from which several anticoagulants are derived, that inhibits hepatic synthesis of vitamin K-dependent coagulation factors.
2. any of these derivatives.
3. see also dicoumarol.
References in periodicals archive ?
Two new dimeric coumarins isolated from Murraya exotica.
coli O157:H7/pCM18 tagged with green fluorescent protein was cultured in 96-well plates (SPL Life Sciences, Korea) with or without coumarins.
9000-10,000), epichlorohydrin, 7-hydroxy coumarin, decanoyl chloride (DC), and FITC-dextran (M.
Biological evaluation of several coumarin derivatives designed as possible anti-inflammatory/antioxidant agents.
Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships.
Chapter 4 describes the varied chemical families found in plants, including the primary metabolites of carbohydrates, lipids, amino acids/proteins, as well as a broad range of secondary metabolites such as alkaloids, coumarins, glycosides, tannins etc.
The amounts of polyphenols ([lambda] = 730 nm), flavonoids ([lambda] = 428 nm), coumarins ([lambda] = 315 nm), anthraquinones ([lambda] = 540 nm), hypericin ([lambda] = 425 nm), and pigments (carotenoids, [lambda] = 455 nm) in herbal teas were determined spectrophotometrically.
Drug interactions: Plant medicines, such as dong quai, which are rich in coumarins may interfere with blood thinners, such as warfarin.
Exploring the consistency of logP estimation for substituted coumarins.
Strawberries contain antioxidant chemicals called coumarins.
But it also contains coumarins, which act as mild blood thinners as well as plant-oestrogen precursors that make it unsuitable for oestrogen-sensitive conditions, including fibroids.