symport

(redirected from Cotransporter)
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symport

 [sim´port]
a transport mechanism that moves two compounds simultaneously across a cell membrane in the same direction, one compound being transported down a concentration gradient and the other against a gradient. See also antiport and cotransport.

sym·port

(sim'pōrt),
Coupled transport of two different molecules or ions through a membrane in the same direction by a common carrier mechanism (symporter). Compare: antiport, uniport.
[sym- + L. porto, to carry]

symport

/sym·port/ (sim´port) a mechanism of transporting two compounds simultaneously across a cell membrane in the same direction, one compound being transported down a concentration gradient, the other against a gradient.

sym·port

(sim'pōrt)
Coupled transport of two different molecules or ions through a membrane in the same direction by a common carrier mechanism (symporter).
Compare: antiport, uniport
[sym- + L. porto, to carry]

symport

a structure that transports two compounds simultaneously across a cell membrane in the same direction, one compound being transported down a concentration gradient, the other against a gradient.
References in periodicals archive ?
The emergence of several new drug classes over the past decade, namely the Glucagon-Like Peptide-1 (GLP-1) receptor agonists, Dipeptidyl Peptidase 4 (DPP-4) inhibitors, and Sodium--Glucose Cotransporter 2 (SGLT-2) inhibitors, has led to considerable market growth.
Similarly, RDX002, a type 2a sodium phosphate cotransporter (NaP2b) inhibitor, is being developed by Sanofi.
The educational session "Directions in Diabetes -- Exploring Options for Patient Care" had expert endocrinologists present the action of DPP-4 enzyme inhibitors and introduced the relatively new Sodium Glucose CoTransporter (SGLT2) inhibitor class of diabetes therapy and presented physician results from the global IntroDia survey.
SLC4A4 encodes a sodium bicarbonate cotransporter involved in the regulation of bicarbonate secretion and absorption, as well as intracellular pH.
Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke.
Canagliflozin (Invokana) is a sodium-glucose cotransporter 2 inhibitor, the first drug in this class to be approved.
AstraZeneca today announced that the Japanese Ministry of Health, Labour and Welfare (MHLW) approved FORXIGAA (dapagliflozin in 5 and 10 mg tablets), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, as a once-daily oral treatment for type 2 diabetes.
Sodium-glucose cotransporter type II inhibitors (SGLT2): from familial renal glucosuria to the treatment of type II diabetes mellitus.
Hereditary hypop-hosphatemic rickets with hypercalciuria is caused by mutations in the sodium-phosphate cotransporter gene SLC34A3.
Gln cotransporter activity was inhibited 75% by TNF-[alpha], exposure.
intraperitoneal, DPO = darbepoietin, Cr = creatinine, TNF-[alpha] = tumour necrosis factor-alpha, IL-2 = interleukin-2, LDH = lactate dehy- drogenase, rHuEPO = recombinant human erythropoietin, PTC = proximal tubule cell, MPO = myeloperoxidase, NAG = N-acetylglutamate, AST = aspartate aminotransferase (indicates reperfusion injury), FENa-fractional excretion of Na+, AQP = aquaporin, NHE = Na+/H+ exchanger, TSC = thiazide-sensitive sodium chloride cotransporter, bcl-2 = oncogene activated by chromosome translocation in human B-cell lymphomas, JNK = c-Jun N-terminal kinase, HSP70 = heat shock protein 70.
Transfer of SW-acclimated flounder to FW reduced gill Na(+),K(+)-ATPase and Na(+),K(+),2Cl(-) cotransporter protein, increased plasma IGF-I, but did not alter hepatic IGF-I mRNA or plasma cortisol levels according to their experiment.