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cosmid |
Also found in: Wikipedia, Hutchinson | 0.29 sec. |
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cosmid a class of plasmid-based vectors carrying the bacteriophage λ cos sequences required for packaging of DNA into phage particles. Used for cloning large DNA fragments (up to 45 kilobases). Recombinant molecules constructed using cosmids are incorporated into bacteriophage using in vitro packaging extracts and introduced with high efficiency into Escherichia coli. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Afterwards, randomly selected cosmids, the so called seed clones, were sequenced up to publication quality. CosMCPrep eliminates this problem, enabling the efficient, fully-automated purification of low copy plasmids such as BACs, cosmids and fosmids. Phrap was originally developed with a more narrow focus as a tool to assist genome centers sequencing cosmids," stated Dr. |
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