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trademark for a preparation of dactinomycin, an antitumor antibiotic.
A trademark for the drug dactinomycin.
a trademark for an antineoplastic (dactinomycin).
Actinomycin DA relatively toxic antibiotic produced by Streptomyces spp, which is used as a chemotherapeutic.
Mechanism Inhibits DNA transcription by RNA polymerase.
Indications Rhabdomyosarcoma, Wilms’ tumour, gestational trophoblastic tumour
Adverse effects Anorexia, nausea, vomiting, myelosuppression with pancytopenia, diarrhoea