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cortisone |
Also found in: Encyclopedia, Wikipedia, Hutchinson | 0.02 sec. |
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cortisone /cor·ti·sone/ (-sōn) a natural glucocorticoid that is metabolically convertible to cortisol; the acetate ester is used as an antiinflammatory and immunosuppressant and for replacement therapy in adrenocortical insufficiency.
Cortisone Glucocorticoid produced by the adrenal cortex in response to stress. Cortisone is a steroid and has anti-inflammatory and immunosuppressive properties. cortisone [kôr′təsōn] a synthetic glucocorticoid. indication It is prescribed for adrenocortical insufficiency inflammation. contraindications Fungal infections or known hypersensitivity to this drug prohibits its systemic use. Viral or fungal infections of the skin, impaired circulation, or known hypersensitivity to this drug prohibits its topical use. adverse effects Among the more serious adverse reactions to the systemic administration of the drug are GI, endocrine, neurologic, fluid, and electrolyte disturbances, so the drug must be used with caution when there are pre-existing conditions. Skin reactions may result from topical administration. Therapy lasting longer than a few days can lead to hypothalamic-pituitary-adrenal suppression. cortisone (17-hydroxy-11-dehydrocorticosterone, Kendall's compound E) (kor´tisōn´), n a hormone produced by the adrenal cortex; a glucocorticoid, 17-hydroxy-11-dehydrocorticosterone; useful in the treatment of rheumatoid arthritis, lupus erythematosus, and some allergic conditions. Has marked antiinflammatory properties. Excess production or administration produces signs of hyperadrenocorticalism (Cushing's syndrome) with hyperlipemia and obesity hyperglycemia and edema. cortisone acetate, n brand name: Cortone; drug class: gluocorticoid, short acting; action: decreases inflammation by suppression of macrophage and leukocyte migration, reduces capillary permeability; uses: inflammation, severe allergy, adrenal insufficiency, collagen, and respiratory and dermatologic disorders. cortisone a glucocorticoid with significant mineralocorticoid activity, isolated from the adrenal cortex; used as an anti-inflammatory agent and for adrenal replacement therapy. cortisone A glucocorticoid derived from cortisol, the term cortisone may be used generically to refer to all synthetic glucocorticoids How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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