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CHOIR
(redirected from Correction of Hemoglobin and Outcomes in Renal Insufficiency)

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
CHOIR
Correction of Hemoglobin and Outcomes in Renal Insufficiency. A trial that studied the use of epoetin alfa treatment to achieve two different target haemoglobin levels in patients with chronic kidney disease
Conclusion The use of a target haemoglobin level of 13.5 g/dl (as compared with 11.3 g/dl) was associated with increased risk and no incremental improvement in the quality of life; the reason is uncertain; theories include some nebulous toxicity from the recombinant epoietin, iron toxicity, and altered blood viscosity, increased platelet activity


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The Correction of Hemoglobin and Outcomes in Renal Insufficiency (CHOIR) study concluded that the use of a target hemoglobin level of 13.
He and his colleagues concluded that considering the expanded use of ACE inhibitors, ARBs, and lipid-lowering drugs, it was "surprising" that only 28% of all patients enrolled in the Correction of Hemoglobin and Outcomes in Renal Insufficiency (CHOIR) trial were on platelet aggregation inhibitors such as aspirin.
 
 
 
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