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Coronaviridae |
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Coronaviridae /Co·ro·na·vi·ri·dae/ (ko-ro?nah-vir´i-de) the coronaviruses: a family of RNA viruses with a positive-sense single-stranded polyadenylated RNA genome, transmitted through contact and other mechanical means. The single genus is Coronavirus. Coronaviridae a family in the order Nidovirales of enveloped, single-stranded, plus sense RNA viruses about 100 nm in diameter. The envelope has prominent droplet-shaped spikes which resemble a solar corona. The two genera are Coronavirus which includes viruses that cause avian infectious bronchitis, hepatitis in mice, transmissible gastroenteritis in swine, canine coronavirus gastroenteritis, bovine coronavirus enteritis in neonatal calves, hemagglutinating encephalitis of pigs, feline infectious peritonitis, turkey bluecomb disease and severe acute respiratory syndrome (SARS) in humans; and Torovirus which includes Breda virus and Berne virus which cause enteric infections in cattle and horses. |
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? Mentioned in | ? References in periodicals archive | |
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MHV is a member of the coronavirus family, Coronaviridae, which includes the virus that causes severe acute respiratory syndrome (SARS), as well as many viruses associated with the common cold. This feature is typical of all Coronaviridae viruses that bud intracellularly at membranes of the intermediate compartment between the endoplasmic reticulum and the Golgi complex, whereas newly assembled virions reach the cell surface by vesicular transport (16). A virus was isolated from the oropharynx of a SARS patient and identified by morphologic characteristics as belonging to the family Coronaviridae (6-8); however, coronaviruses had not been a prime consideration in the differential diagnosis since they rarely cause lower respiratory tract infections in humans (9-11). |
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