corepressor

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Related to Corepressor (genetics): coactivator, aporepressor

corepressor

 [ko″re-pres´ser]
a small molecule that combines with a protein aporepressor molecule to form an active substance, which then binds to an operator gene and inhibits the synthesis of an enzyme.

co·re·pres·sor

(kō'rē-pres'ŏr),
A molecule, usually a product of a specific metabolic pathway (for example, nuclear protein), which combines with and activates a repressor produced by a regulator gene. The activated repressor then attaches to an operator gene site and inhibits activity of the structural genes. This homeostatic mechanism negatively regulates enzyme production in repressible enzyme systems.

corepressor

/co·re·pres·sor/ (ko″re-pres´er) in genetic theory, a small molecule that combines with an aporepressor to form the complete repressor.

corepressor

(kō′rĭ-prĕs′ər)
n.
A substance that combines with and activates a genetic repressor, thus preventing gene transcription and inhibiting protein synthesis.

co·re·pres·sor

(kō'rĕ-pres'ŏr)
A molecule, usually a product of a specific metabolic pathway, which combines with and activates a repressor produced by a regulator gene. The repressor then attaches to an operator gene site and inhibits activity of the structural genes. This homeostatic mechanism regulates enzyme production in repressible enzyme systems.

corepressor

a substance of low molecular weight which unites with an APOREPRESSOR and reduces the activity of particular structural genes (see OPERON MODEL).

corepressor

a substance (e.g. the product of a metabolic pathway) that activates a repressor by combining with it.