The purified protein is treated in phosphate buffer with formaldehyde and then coprecipitated
with alum (potassium aluminum sulfate) to form bulk vaccine adjuvanted with amorphous aluminum hydroxyphosphate sulfate.
This can be attributed to creation of multi-modal voids when the coprecipitated
nanocomposites are compression molded.
Typically, sequence-specific proteases are used to break up the proteins into peptides that are coprecipitated
with a light-absorbing matrix such as dihydroxy benzoic acid.
They extracted a protein from the sera of patients with pneumococcal pneumonia that coprecipitated
with the C polysaccharide derived from the cell wall of the pneumococcus.
The polymer solution was coprecipitated
in ethanol drop by drop with vigorous agitation, and the white precipitates were repeatedly washed with ethanol, water and acetone.