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cooperativity |
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cooperativity /co·op·er·a·tiv·i·ty/ (ko-op″er-ah-tiv´ĭ-te) the phenomenon of alteration in binding of subsequent ligands upon binding of an initial ligand by an enzyme, receptor, or other molecule with multiple binding sites; the affinity for further binding may be enhanced (positive c.) or decreased (negative c.) . cooperativity interaction between some proteins in which the binding of one may increase or decrease binding of the other. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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argentatum, negative cooperativity inhibits the chain transfer reaction across a wide range of FPP concentrations, a property possessed in far less degree by H. Long-range cooperativity due to C5-propynylation of oligopyrimidines enhances specific recognition by uridine of ribo-adenosine over ribo-guanosine. Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants. |
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