constitutional delay of stature

(redirected from Constitutional growth delay)
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constitutional delay of stature

slowed growth during the first 2-3 years of life, normal or near normal growth after, family history with similar findings, bone age below chronologic age, with resultant predicted adult height in the context of the family pattern.
References in periodicals archive ?
g familial short stature, constitutional growth delay, congenital heart disease, tuberculosis, celiac disease, immunodeficiency etc were excluded from the study.
Short stature can be due to a variety of genetic or endocrine disorders, chronic diseases, familial short stature, or constitutional growth delay.
A child with constitutional growth delay also has a negative medical evaluation looking for underlying reasons for short stature and typically has delayed bone age.
We excluded all patients with familial short stature, constitutional growth delay, hormone deficiency, malnutrition, and chronic systemic disorders, and included healthy patients with thalassemia minor.
In addition, chromosomal disorders such as Turner's syndrome; intrauterine growth retardation; endocrine disorders; or, simply, familial short stature or constitutional growth delay can cause a child to grow at a slower than average rate.
In addition, chromosomal disorders such as Turner's syndrome, intrauterine growth retardation, endocrine disorders, or simply familial short stature or constitutional growth delay can cause a child to grow at a slower than average rate.
I shall take the position that there is an entitlement to GH in those situations where children (1) are growth hormone deficient, (2) have other medical problems impinging on growth, or (3) have pathological rates of growth--but that there is no entitlement where children have a constitutional growth delay, or are very short but not GHD or otherwise pathological.
They are not functionally equivalent to very short children whose growth velocity is in the normal range nor are they equivalent to children with constitutional growth delay.
In contrast, children with constitutional growth delay often have a period of slow growth during infancy or childhood, then resume normal growth, and usually reach an adult height consistent with their genetic heritage.
Pediatricians are generally reluctant to treat constitutional growth delay with growth hormone.
Endocrine causes of short stature include, isolated growth hormone deficiency, hypothyroidism, multiple pituitary deficiencies and GH resistant syndromes", The non-endocrine causes like malnutrition, intrauterine growth retardation with no "catch up" growth, constitutional growth delay, cystic fibrosis, blood disorders should always be ruled out before making a diagnosis of growth hormone insensitivity or Laron type dwarfism".
While panel members overwhelmingly approved recommending a broader indication for Humatrope in an 8-2 vote, they had strong concerns about screening out patients who may simply have constitutional growth delay and not non-GHD short stature.
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