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conivaptan

   Also found in: Wikipedia 0.01 sec.
conivaptan,
a vasopressin receptor antagonist.
indications This drug is used to treat euvolemia hyponatremia in those hospitalized.
contraindications Hypovolemia and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include headache, confusion, insomnia, hypotension, hypertension, orthostatic hypotension, phlebitis, nausea, vomiting, constipation, dry mouth, hematuria, polyuria, urinary tract infection, pollaklura, anemia, erythemia, injection site reaction, dehydration, hyperglycemia, hypoglycemia, hypokalemia, hypomagnesia, hyponatremia, oral candidiasis, pain, peripheral edema, and pneumonia. Atrial fibrillation is a life-threatening side effect.


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The 100mL, single-use premixed formulation of Vaprisol comes in a plastic INTRAVIA(R) Container, a product of Baxter Healthcare Corporation, containing 20mg of conivaptan hydrochloride in 5% dextrose solution.
SAN FRANCISCO -- Satavaptan and conivaptan appear to be effective in the treatment of dilutional hyponatremia, a frequent consequence of heart failure and of renal failure.
Other investigators assessed conivaptan (Vaprisol, Astellas) and supported its use for euvolemic hyponatremia because the drug increased urine output of mostly free water with little electrolyte loss (J.
 
 
 
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