hyperinsulinaemic hypoglycaemia type 5

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Related to Congenital hyperinsulinism: Congenital hypothyroidism

hyperinsulinaemic hypoglycaemia type 5

An autosomal dominant condition (OMIM:609968) characterised by persistent hypoglycaemia in infancy due to defective negative feedback regulation of insulin secretion by low serum glucose levels.
 
Molecular pathology
Defects of INSR cause hyperinsulinaemic hypoglycaemia type 5.
References in periodicals archive ?
Congenital hyperinsulinism is one of the indications we are considering for a Phase 2 study, which we expect to initiate later this year.
Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism.
All the children had congenital hyperinsulinism that could not be controlled with medicine.
May 27 /PRNewswire/ -- Researchers from The Children's Hospital of Philadelphia successfully cured 91 percent of infants of a rare but serious condition called focal congenital hyperinsulinism (HI).

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