Congenital Pain Insensitivity

Congenital Insensitivity to Pain with Anhidrosis

A neurologic disorder characterised by impaired nociception with intact cognition and sensation including discriminative touch. While these patients may be mildly retarded, there are no detectable physical abnormalities. Children with CIPA often bite their tongues, suffer corneal damage and may be unaware of fractures
Aetiology Some cases are due to excessive endophin production for which naloxone may be effective. In others, one of several loss-of-function mutations have been identified in the voltage-gated sodium channel SCN9A, preventing forward propagation of nociceptive information to the brain. While it is very rare, CIPA is more common in consanguineous populations including one cohort in northern Sweden and another in Ashkenazi Jews

Mentioned in	?		References in periodicals archive	?		Medical browser	?		Full browser	?
No references found	Further provided are therapeutic methods for treating disease states including, but not limited to, chronic pain syndromes, congenital pain insensitivity, inflammation, ischemia, host defense dysfunction, immune surveillance dysfunction, arthritis, multiple sclerosis, autoimmunity, immune dysfunction, and allergy. ARCH obtains United States patent by BIOTECH Patent News	congenital herpes congenital hip dislocation Congenital Hip Dysplasia congenital hypernatremia congenital hypertrophy of the retinal pigment epithelium congenital hypogammaglobulinemia congenital hypoplastic anemia congenital hypothyroidism congenital ichthyosiform erythroderma congenital immunity Congenital Insensitivity to Pain with Anhidrosis congenital jaundice congenital laryngeal stridor congenital leukemia congenital leukemoid reaction congenital lobar emphysema congenital lymphedema congenital malformation Congenital Malignancy congenital megacolon congenital myxedema congenital nevus congenital nonspherocytic hemolytic anemia congenital nystagmus congenital oculofacial paralysis Congenital Pain Insensitivity congenital pancytopenia congenital paramyotonia congenital platelet function defect congenital polycystic disease congenital pouch colon congenital pulmonary arteriovenous fistula congenital pyloric stenosis congenital reduced phalanges congenital rubella syndrome congenital scleral crescent congenital scoliosis congenital short neck syndrome congenital sternal foramina congenital stridor congenital subluxation of the hip congenital syphilis congenital total lipodystrophy congenital toxoplasmosis congenital tremor syndrome Congenital Ureter Anomalies congenital valve Congest congested congestion congestive	congenital neutropenia congenital neutropenia congenital neutropenia congenital nevus Congenital Nevus-Like Nevi congenital night blindness congenital night blindness congenital night blindness Congenital Non-Spherocytic Haemolytic Anaemia Congenital Nonbullous Ichthyosiform Erythroderma congenital nonspherocytic hemolytic anemia congenital nonspherocytic hemolytic anemia congenital nonspherocytic hemolytic anemia Congenital Nonspherocytic Hemolytic Disease congenital nystagmus congenital nystagmus congenital nystagmus congenital nystagmus congenital oculofacial paralysis Congenital Oculomotor Apraxia congenital of newborn epulis congenital of newborn epulis congenital of newborn epulis Congenital Onychodysplasia of the Index Finger Congenital Optic Nerve Hypoplasia Congenital or Early-Onset Hearing Impairment Congenital osteosclerosis Congenital osteosclerosis Congenital osteosclerosis Congenital Ovine Neuronal Ceroid Lipofuscinosis Congenital Pain Insensitivity congenital pancytopenia congenital pancytopenia congenital paralysis congenital paralysis congenital paralysis congenital paralysis congenital paramyotonia congenital pastern flexure congenital pastern flexure congenital pastern flexure congenital pathology Congenital Penile Urethrocutaneous Fistula Congenital pes planus Congenital Pilar and Smooth Muscle Nevus congenital platelet function defect Congenital pneumonia Congenital pneumonia Congenital pneumonia congenital polycystic disease Congenital polycystic disease of kidney Congenital polycystic disease of kidney congenital pouch colon congenital pouch colon congenital pouch colon congenital preauricular cyst congenital preauricular cyst congenital preauricular cyst Congenital problems Congenital problems congenital pulmonary arteriovenous fistula

Mentioned in

References in periodicals archive

Medical browser

Full browser

No references found

Further provided are therapeutic methods for treating disease states including, but not limited to, chronic pain syndromes, congenital pain insensitivity, inflammation, ischemia, host defense dysfunction, immune surveillance dysfunction, arthritis, multiple sclerosis, autoimmunity, immune dysfunction, and allergy.

Congenital Insensitivity to Pain with Anhidrosis (redirected from Congenital Pain Insensitivity)

Congenital Insensitivity to Pain with Anhidrosis
(redirected from Congenital Pain Insensitivity)