conformation

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Related to Conformations: confirmations

con·for·ma·tion

(kon'fōr-mā'shŭn),
The spatial arrangement of a molecule achieved by rotation of groups about single covalent bonds, without breaking any covalent bonds; the latter restriction differentiates conformation from configuration (as in anomers and related stereoisomers) where a bond or bonds must be broken in going from one form (configuration) to another. Conformation is one of the most important aspects of sugar chemistry and is basic to an understanding of the chemical properties of sugars. Compare: configuration.

con·for·ma·tion

(kon'fōr-mā'shŭn)
The spatial arrangement of a molecule achieved by rotation of groups about single covalent bonds, without breaking any covalent bonds.
Compare: configuration

conformation

(kŏn″for-mā′shŭn)
The form or shape of a part, body, material, or molecule.

conformation

symmetry, size and shape of the various body regions relative to each other or the general appearance of the animal in terms of satisfying the observer's appreciation of what is a desirable appearance. Most breed societies issue lists of desirable and undesirable points of conformation. Most of them are desirable. Some are not and react adversely on the animals' well-being. Desirable conformation may also be indicated by diagrams or photographs.
Also may refer to the spatial arrangement of atoms in a molecule.

mitochondrial conformation
mitochondria may be in an abnormal state of condensed conformation, detected by comparison with mitochondria of orthodox status; orthodox conformation is linked to inactive oxidase phosphorylation, condensed to active phosphorylation.
References in classic literature ?
My host, however, had in some degree resumed the calmness of his demeanor, and questioned me very rigorously in respect to the conformation of the visionary creature.
Yet I did not heed the bleakness of the weather; I was better fitted by my conformation for the endurance of cold than heat.
As Miggs, however, was deaf to all entreaties, Mr Tappertit leant her against the wall as one might dispose of a walking-stick or umbrella, until he had secured the window, when he took her in his arms again, and, in short stages and with great difficulty--arising from her being tall and his being short, and perhaps in some degree from that peculiar physical conformation on which he had already remarked--carried her upstairs, and planting her, in the same umbrella and walking-stick fashion, just inside her own door, left her to her repose.
Mr Merdle, left alone to meditate on a better conformation of himself to Society, looked out of nine windows in succession, and appeared to see nine wastes of space.
Being an orphan of a chubby conformation, he then took to rolling, and had rolled into the gutter before they could come up.
Udder conformations with big or extremely positioned teats and droopy udders were linked to an increase in teat lesions, udder lumps, acute mastitis or slower growing lambs.
Objective: "We use computational and analytical methods to study the factors that determine charge state of macromolecules in droplet, gaseous and bulk environments and the relation of the charge state to the conformations of the macromolecules.
The Heptares platform is nucleated around its unique ability, using its StaR technology, to stabilise GPCRs in precisely defined, biologically-relevant conformations.
When ligands bind to a specific subset of receptors, the ligands stabilize specific protein conformations, turning on (or off) molecular switches that control diverse cellular functions.
This platform was designed for the systematic discovery of novel peptides that block proteins of interest from achieving certain disease-associated conformations, a capability that represents immense therapeutic promise in numerous fields.
We found evidence for strong intramolecular band structure [7], but this does not provide a clear indication of the type of dipole ordering along the surface normal: both an all-trans and some type of alternating trans-gauche conformations are possible from the experimental band mapping data.
The conformations that favored esters with an axial position (trans-1,3-CHDA and cis-1,4-CHDA) had lower hydrolytic velocity than conformations that favored an equatorial ester position.