keratoconus

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keratoconus

 [ker″ah-to-ko´nus]
conical protrusion of the central part of the cornea, resulting in an irregular astigmatism.
Keratoconus. From Dorland's, 2000.

ker·a·to·co·nus

(ker'ă-tō-kō'nŭs), [MIM*148300]
A conic protrusion of the cornea caused by thinning of the stroma; usually bilateral.
See also: Fleischer ring, Munson sign.
Synonym(s): conic cornea
[kerato- + G. kōnos, cone]

keratoconus

/ker·a·to·co·nus/ (-ko´nus) conical protrusion of the central part of the cornea.

keratoconus

[ker′ətōkō′nəs]
Etymology: Gk, keras + konos, cone
a noninflammatory protrusion of the central or paracentral region of the cornea. It is worse in allergy sufferers and may result in marked irregular astigmatism. It is also associated with Down syndrome. Gas permeable contact lenses often significantly improve visual acuity as compared with spectacles, although a corneal transplant is indicated in about 15% of patients with this condition. The cause of the condition is unknown, but it likely has a genetic basis.

ker·a·to·co·nus

(ker'ă-tō-kō'nŭs)
A conic protrusion of the cornea caused by thinning of the stroma; usually bilateral.
See also: Fleischer ring, Munson sign
Synonym(s): conic cornea.
[kerato- + G. kōnos, cone]

keratoconus

A growth disorder (dystrophy) of the CORNEA causing central peaking or conicity and affecting vision. The main disability is from image distortion. Keratoconus is a familial condition that usually starts in adolescence, affecting girls more than boys. Spectacles may help at first, the progressive distortion usually calls for correction with hard contact lenses. Corneal grafting is often eventually required but the results are usually good.

Keratoconus

An eye condition in which the cornea bulges outward, interfering with normal vision. Usually both eyes are affected.

keratoconus (KC)

A developmental anomaly in which the central portion of the cornea becomes thinner and bulges forward in a cone-shaped fashion. Two types of cones are commonly described: a round cone and an oval (or sagging) cone. It usually appears around puberty, is bilateral, although one eye may be involved long before the other. Other corneal signs may be Vogt's striae, Fleischer's ring, scarring and corneal hydrops, as well as myopia and irregular astigmatism. The condition may be associated with osteogenesis imperfecta, ectopia lentis, aniridia, retinitis pigmentosa, Down's syndrome, Ehlers-Danlos syndrome, Marfan's syndrome. The main symptom is a loss of visual acuity due to irregular astigmatism and myopia. Correction is usually best achieved with contact lenses, especially rigid gas permeable, but if these cannot be worn or the condition is very severe, a corneal transplant is carried out (Fig. K1). Syn. conical cornea. See central corneal clouding; pellucid marginal degeneration; corneal ectasia; acute hydrops; keratoscope; combination lens; piggyback lens; lenticonus; blue sclera; Munson's sign; Rizzuti's sign; stria; corneal topography.
Fig. K1 Schematic diagram of a keratoconus corneaenlarge picture
Fig. K1 Schematic diagram of a keratoconus cornea

Table K1 Differential diagnosis between keratoconus and related thinning disorders. (Adapted from Krachmer JH, Feder RS, Belin MW. Surv Ophthalmol 1984; 28:293-322)
keratoconuspellucid marginal degenerationkeratoglobusposterior keratoconus
frequencymost commonless commonrareleast common
lateralityusually bilateralbilateralbilateralusually unilateral
age of onsetpuberty/early adulthoodAge 20 to 40susually at birthbirth
corneal thinningcentral or paracentralinferior crescent-shaped band 1-2 mm widegeneralized and slightly more in peripheryparacentral posterior excavation
protrusionapicalabove band of thinninggeneralizednone
iron line
(Fleischer's ring)
commonrarenoneoccasional
scarringcommononly after hydropsrarecommon
progressionyesyesusually nono
induced astigmatismirregularhigh, irregular and varies with locationnonevery slight effect

keratoconus

conical protrusion of the central part of the cornea.

Patient discussion about keratoconus

Q. Has anyone had experience with a corneal transplant because of keratoconus?

A. my uncle had to do a transplant- it took 5 weeks until he could see anything , another year to get his vision straightened up. but now he is fine! i know that he looked for information in the "National Keratoconus Foundation". they were very helpful (and nice!), they have a website with information on all forms of treatment:
http://www.nkcf.org/

good luck :)

More discussions about keratoconus