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competitive antagonist |
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competitive antagonist, a substance that interferes with usual metabolic activity by competing for binding sites on a substrate (the substance on which an enzyme acts in a chemical reaction) or on an enzyme that ordinarily attacks the substrate. The antagonist is usually an analog of the substrate. See also antimetabolite. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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NK4 is an elastase-generated fragment of hepatocyte growth factor (HGF) containing four kringle domains, initially discovered as a competitive antagonist of HGF. We have demonstrated that fenitrothion acts as an AR competitive antagonist in vitro and inhibits the development of androgen-dependent tissues in vivo (Tamura et al. |
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