Spending a nauseous month on Combivir
, I became aware that HIV had come to visit me and my family.
Zidovudine and lamivudine are sold as Combivir
by a subsidiary of the U.
At this time, I am taking the medications Reyataz, Combivir
, and Norvir.
They start with 11 current products, including GSK's Combivir
and Pfizer's Selzentry with six more in development.
Glaxo will supply more than 90,000 treatment packs of its drugs - Combivir
, Epivir and Ziagen - to the Russian Government by the end of 2006.
GlaxoSmithKline was also in focus as three of its drugs, Epzicom, Combivir
and Lexiva were included in the approved treatment guidelines of the International Aids Society-USA for initial antiretroviral therapy.
Combination therapy with Sustiva, Viread, and Emtriva was superior to combined Sustiva and Combivir
for treating HIV in treatment-naive patients enrolled in a phase III trial.
Schering-Plough had terminated this study in October 2005 when patients who received vicriviroc in combination with Combivir
experienced virologic breakthrough, compared to those who received the control regimen of Combivir
and efavirenz, a current standard of care for treatment-naive patients living with HIV.
But a study comparing Combivir
plus efavirenz with Combivir
plus vicriviroc in patients who were treatment naive was terminated early because of the clear superiority of efavirenz.
Vicriviroc: Schering-Plough and the ACTG stopped low-dose arms in their trials, and later Schering-Plough stopped its treatment-naive trial entirely, because the volunteers receiving vicriviroc plus Combivir
were not controlling the virus as well as those in a comparison arm receiving efavirenz plus Combivir
The first was Combivir
, which is a combination of zidovudine (Retrovir, AZT) and lamivudine (Epivir, 3TC).
In a separate study, Palmer and her colleagues compared rates of nevirapine resistance in 10 women who had received single-dose nevirapine only and 22 similar women who had also received either 4 or 7 days of Combivir
, a drug that contains zidovudine and lamivudine, following delivery.