combined immunodeficiency

(redirected from Combined immunodeficiencies)
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com·bined im·mu·no·de·fi·cien·cy

immunodeficiency of both B and T lymphocytes.

com·bined im·mu·no·de·fi·cien·cy

(kŏm-bīnd' im'yū-nō-dĕ-fish'ĕn-sē)
Immunodeficiency of both the B-lymphocytes and T-lymphocytes.

immunodeficiency

a deficiency in the immune system, either that mediated by antibody or T lymphocytes, or both. See also agammaglobulinemia, hypogammaglobulinemia, feline immunodeficiency virus, bovine immunodeficiency virus.

acquired immunodeficiency
see immune deficiency disease.
cancer-associated immunodeficiency
in general, associated with cachexia and debilitation, and also related to the type of neoplasia. Tumor-related effects on the immune system include impaired function of lymphocytes, altered cytokine production and activation of suppressor cell functions.
combined immunodeficiency
common variable immunodeficiency
a term encompassing a heterogeneous group of syndromes, which may be inherited or acquired, characterized by recurring persistent infections and deficiencies of some of the immunoglobulin classes.
congenital immunodeficiency
see immune deficiency disease.
immunodeficiency disease
iatrogenic immunodeficiency
secondary immune deficiency disease.
severe combined immunodeficiency
X-linked immunodeficiency
an inherited form of severe combined immunodeficiency has been reported in dogs. Puppies fail to grow and die from overwhelming infections at an early age.
References in periodicals archive ?
Octagam is indicated for treatment of primary humoral immunodeficiency (such as congenital agammaglobulinemia), common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.
Of 946 patients with primary immunodeficiency, including 29 with severe combined immunodeficiencies, diagnosed from 1980 through 2006 at the Children's Memorial Health Institute in Warsaw, adverse events after BCG vaccination were observed in 16 (8,9).
This includes, but is not limited to, the humoral immune defect in common variable immunodeficiency (CVID), X-linked agammaglobulinemia, congenital agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.
octagam is an immune globulin intravenous (human) 5% liquid indicated for treatment of primary humoral immunodeficiency (PI), such as congenital agammaglobulinemia, common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome and severe combined immunodeficiencies.
These include but are not limited to congenital X-linked agammaglobulinemia, common variable immunodeficiency, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.
Until recently, a correct diagnosis for babies born with SCID or other combined immunodeficiencies, such as DOCK2 deficiency, could be made only after these babies had developed serious infections, which could lead to death or compromise the efficacy of an HSCT," said Notarangelo, who is a professor of pediatrics at Harvard Medical School.
octagam 5% is an immune globulin intravenous (human liquid indicated for treatment of primary humoral immunodeficiency (PI), such as congenital agammaglobulinemia, common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome and severe combined immunodeficiencies.

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