hyperlipidemia (redirected from Combined hyperlipidemia)

hyperlipidemia /hy·per·lip·id·emia/ (-lip″ĭ-de´me-ah) elevated concentrations of any or all of the lipids in the plasma, including hypertriglyceridemia, hypercholesterolemia, etc.hyperlipide´mic

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combined hyperlipidemia  a generic designation for a hyperlipidemia in which several classes of lipids are elevated; usually used to denote the phenotype of a type II-b hyperlipoproteinemia.

familial combined hyperlipidemia  an inherited disorder of lipoprotein metabolism manifested in adulthood as hypercholesterolemia, hypertriglyceridemia, or a combination, with elevated plasma apolipoprotein B and premature coronary atherosclerosis.

mixed hyperlipidemia  see under hyperlipemia.

remnant hyperlipidemia  a form in which the accumulated lipoproteins are normally transient intermediates, chylomicron remnants, and intermediate-density lipoproteins; a generic descriptor for the type III hyperlipoproteinemia phenotype.

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hy·per·lip·i·de·mi·a (hpr-lp-dm-) or hy·per·lip·oi·de·mi·a (-lpoi-dm-)

n.

An excess of lipids in the blood. Also called hyperlipemia, lipemia, lipidemia.

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Hyperlipidemia

A general term for elevated concentrations of any or all of the lipids in the plasma.

Mentioned in: Obesity, Retinal Vein Occlusion

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hyperlipidemia

[-lip′idē′mē·ə]

Etymology: Gk, hyper + lipos, fat, haima, blood

an excess of lipids, including glycolipids, lipoproteins, and phospholipids, in the plasma. Also spelled hyperlipidaemia. See also antilipidemic.

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hyperlipidemia [hi″per-lip″i-de´me-ah]

elevated concentrations of any or all of the lipids in the blood. Called also hyperlipemia and lipemia.

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hyperlipidemia,

n an excess of lipids in the plasma, including the glycolipids, lipoproteins, and phospholipids.

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hyperlipidemia

a general term for elevated concentrations of any or all of the lipids in the plasma. See also hyperlipoproteinemia.

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postprandial hyperlipidemia

a normal increase following ingestion of food.

primary hyperlipidemia

caused by decreased activity of lipoprotein lipase, it occurs in miniature Schnauzer dogs.

secondary hyperlipidemia

may occur in association with diabetes mellitus, hypothyroidism, pancreatitis, hyperadrenocorticism, cholestatic liver disease and nephrotic syndrome.

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hyperlipidemia

An ↑ of circulating lipids–fatty acids, TGs, and cholesterol, often linked to ↑ lipoproteins–hyperlipoproteinemia and/or ↓ degradative enzymes–eg, lipoprotein lipase. See Acquired hyperlipidemia, Familial combined hyperlipidemia.

Hyperlipidemia

Primary Dyslipidemia intimately linked to CAD

Secondary

• Secondary hypercholesterolemia, seen in acute intermittent porphyria, cholestasis, hypothyroidism and pregnancy

• Secondary hypertriglyceridemia, seen in DM, acute alcohol intoxication, acute pancreatitis, gout, gram-negative sepsis, glycogen storage disease I, oral contraceptive use

• Combined hypercholesterolemia & hypertriglyceridemia, seen in nephrotic syndrome, chronic renal failure, corticosteroid therapy and immunosuppression

Note: 30-40% of the population is sensitive to dietary cholesterol and ↑ dietary cholesterol may ↑ cholesterol in the circulation