coloboma

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coloboma

 [kol″o-bo´mah] (pl. colobomas, colobo´mata) (L.)
1. a defect of tissue.
2. particularly, a defect of some ocular tissue, usually due to failure of part of the fetal fissure to close; it may affect the choroid, ciliary body, eyelid (palpebral coloboma, colobo´ma palpebra´le), iris (colobo´ma i´ridis), lens (colobo´ma len´tis), optic nerve, or retina (colobo´ma re´tinae). A scotoma is usually present, corresponding to the area of the coloboma.
Coloboma of the iris. From Dorland's, 2000.

col·o·bo·ma

(kol-ō-bō'mă),
Any defect, congenital, pathologic, or artificial, especially of the eye due to incomplete closure of the retinal fissure.
[G. kolobōma, lit., the part taken away in mutilation, fr. koloboō, to dock, mutilate]

coloboma

/col·o·bo·ma/ (kol″o-bo´mah) pl. colobomas, colobo´mata   [L.]
1. an absence or defect of tissue.
2. a defect of ocular tissue, due to failure of part of the fetal fissure to close; it may affect the choroid, ciliary body, eyelid, iris, lens, optic nerve, or retina.

bridge coloboma  coloboma of the iris in which a strip of iris tissue bridges over the fissure.
Fuchs' coloboma  a small, crescent-shaped defect of the choroid at the lower edge of the optic disk.
coloboma lo´buli  fissure of the ear lobe.

coloboma

(kŏl′ə-bō′mə)
n. pl. colobo·mata (-mə-tə)
An anomaly of the eye, usually a developmental defect, that often results in some loss of vision.

col′o·bo′ma·tous adj.

coloboma

[kol′əbō′mə] pl. colobomas, colobomata
Etymology: Gk, koloboma, defect
a congenital or pathological defect in the ocular tissue of the body, usually affecting the iris, ciliary body, or choroid by forming a cleft that extends inferiorly. Colobomas are usually the result of the failure of part of the fetal fissure to close. colobomatous, adj.
enlarge picture
Coloboma

col·o·bo·ma

(kol'ō-bō'mă)
Any defect, congenital, pathologic, or artificial, especially of the eye due to incomplete closure of the optic fissure.
[G. kolobōma, lit., the part taken away in mutilation, fr. koloboō, to dock, mutilate]

coloboma

A congenital gap in a part, especially in the IRIS or CHOROID of the eye or in an eyelid.

coloboma 

Congenital, pathological or operative anomaly in which a portion of the structure of the eye is lacking, e.g. coloboma of the choroid, coloboma of the eyelid, coloboma of the iris, coloboma of the lens, coloboma of the retina, etc. Typical colobomas result from defective closure of the embryonic fissure of the optic cup. Congenital iris colobomas are usually located inferiorly. They are often associated with Crouzon's syndrome (Fig. C13). Lid colobomas are commonly associated with Treacher-Collins syndrome. Coloboma of the optic disc is characterized by a glistening, white excavation, decentred inferiorly. It is sometimes confounded with glaucomatous cupping, especially when it is accompanied by a field defect. The condition is often associated with microphthalmia and several syndromes (e.g. Edward's syndrome, Patau's syndrome).
Fig. C13 Coloboma of the irisenlarge picture
Fig. C13  Coloboma of the iris

coloboma

an apparent absence or defect of some ocular tissue, usually due to failure of a part of the fetal fissure to close; it may affect the choroid, ciliary body, eyelid (palpebral coloboma, coloboma palpebrale), iris (coloboma iridis), lens (coloboma lentis), optic nerve or retina (coloboma retinae). Colobomas of the choroid are common in cattle, and have been observed in miniature swine. Colobomas of the optic disk are an inherited defect in several breeds of cattle.

atypical coloboma
on occurring at a location other than the fetal fissure.
iris coloboma
a full thickness defect in the iris. When it occurs at the base of the iris, it is called iridodiastasis.
optic nerve coloboma
part of the scleral ectasia syndrome in dogs; also seen in Basenji dogs and Charolais cattle.
typical coloboma
one occurring in or near to the fetal cleft.

Patient discussion about coloboma

Q. My grandson 5mths has been dignosed with Coloboma HAs anyone had any experiences with this. He will be seen at Toronto Hospital for Sick Kids

A. Don't have it or a child with it, so I can't add from my own experience. However, here are several places in which you can find more information about this:

http://en.wikipedia.org/wiki/Coloboma
http://www.nlm.nih.gov/medlineplus/ency/article/003318.htm

More discussions about coloboma
References in periodicals archive ?
Objective: To evaluate the anatomical and visual outcome of surgical management of retinal detachment associated with chorio-retinal coloboma.
Orbita: distopia orbitaria (mala posicion), dermoides epibulbares, anoftalmia/microftalmia, blefaroptosis, coloboma retinal o coroidal, entre otras anomalias menos frecuentes.
Colobomas can occur as an isolated congenital abnormality or as part of a syndromic setting, including CHARGE (Coloboma, Heart malformations, choanal AtResia, Growth and/or mental retardation, genital anomalies, Ear anomalies and/or deafness), VATER (Vertebrae, Anus, Trachea, Esophagus, and Renal), branchio-oculo facial, Meckel-Gruber, Walker-Warburg, and Goldenhar syndromes; Aicardi, basal cell nevus; and Trisomy 13 and 18.
Paciente de sexo femenino atendida a la edad de 3 anos en el servicio de Consulta externa de Genetica en el Instituto de Ortopedia Infantil Roosevelt (Bogota, Colombia) por historia de coloboma de nervio optico bilateral, presencia de hemangiomas congenitos en rostro que han perdido pigmentacion con el paso del tiempo, retardo psicomotor y baja talla.
La resonancia magnetica cerebral (RM) practicada en el mes siguiente revelo agenesia total del cuerpo calloso, hemiatrofia cerebral izquierda, displasia cortical, heterotopias periventriculares, y coloboma del nervio optico (Fig.
Coloboma of the eye is a cleft or failure of closure during development of the eyeball.
People with colobomas of the iris are suitable candidates for cataract surgery--and so are older individuals.
Less common abnormalities include various ocular problems, such as congenital cataracts and colobomas.
He has colobomas that affect his central vision so that he often tilts his head to get a better view.
NewIris was originally developed to help patients suffering from oculocutaneous albinism (lack of pigment in eyes and skin) and colobomas (abnormal iris and pupils structure).