Also found in: Dictionary, Encyclopedia.
an antibacterial and steroid agent.
indications It is prescribed topically in the treatment of infections of the outer ear and systemically for the treatment of serious gram-negative infections and gastroenteritis caused by Escherichia coli.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious systemic reactions are respiratory arrest, renal toxicity, and neuromuscular blockade.
Polymyxin E; an antibiotic effective against some gram-negative bacteria, esp. Pseudomonas organisms, that are resistant to other antibiotics.