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colesevelam

   Also found in: Wikipedia 0.01 sec.
colesevelam /co·le·sev·e·lam/ (ko″lĕ-sev´ĕ-lam) a bile acid–binding polymer that decreases serum levels of total cholesterol, LDL cholesterol, and apolipoprotein B and increases levels of HDL cholesterol; used as the hydrochloride salt in the treatment of primary hypercholesterolemia.
colesevelam
[ko′lesev′elam]
a polymer that binds bile acids in the intestine and prevents them from being reabsorbed, resulting in decreased serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and apolipoprotein B and increased levels of high-density lipoprotein cholesterol. It is administered orally as the hydrochloride salt. It is an adjunctive therapy to reduce elevated LDL-C levels in patients with primary hypercholesterolemia.

colesevelam [ko″lĕ-sev´ĕ-lam]
a polymer that binds bile acids in the intestine and prevents them from being reabsorbed, resulting in decreased serum levels of total cholesterol, LDL cholesterol (LDL-C), and apolipoprotein B and increased levels of HDL cholesterol (HDL-C); administered orally as the hydrochloride salt as adjunctive therapy to reduce elevated LDL-C levels in patients with primary hypercholesterolemia.


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A newer, specifically engineered BAS, colesevelam HCl, is a hydrophilic polymer taken as a tablet.
SEATTLE -- The LDL cholestorol-lowering agent colesevelam also lowers blood glucose levels significantly in type 2 diabetes patients already on oral diabetes medication, according to two studies presented at the annual meeting of the American Association of Clinical Endocrinologists.
Three BAS are currently used for treating hypercholesterolemia in the United States: the conventional sequestrants, cholestyramine and colestipol, and the specifically engineered BAS, colesevelam hydrochloride (HCl).
 
 
 
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