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colesevelam |
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colesevelam /co·le·sev·e·lam/ (ko″lĕ-sev´ĕ-lam) a bile acid–binding polymer that decreases serum levels of total cholesterol, LDL cholesterol, and apolipoprotein B and increases levels of HDL cholesterol; used as the hydrochloride salt in the treatment of primary hypercholesterolemia. colesevelam [ko′lesev′elam] a polymer that binds bile acids in the intestine and prevents them from being reabsorbed, resulting in decreased serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and apolipoprotein B and increased levels of high-density lipoprotein cholesterol. It is administered orally as the hydrochloride salt. It is an adjunctive therapy to reduce elevated LDL-C levels in patients with primary hypercholesterolemia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Three BAS are currently used for treating hypercholesterolemia in the United States: the conventional sequestrants, cholestyramine and colestipol, and the specifically engineered BAS, colesevelam hydrochloride (HCl). 5 mg daily, oxycodone 40 mg twice daily, venlafaxine 150 mg twice daily, and colesevelam 1,875 mg twice daily. 31) The introduction of new agents such as the recently launched colesevelam hydrochloride may provide more acceptable alternatives to traditional resins. |
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