Cold agglutinins


Also found in: Wikipedia.

Cold agglutinins

Antibodies that cause clumping of red blood cells when the blood temperature falls below normal body temperature (98.6°F/37°C).
Mentioned in: Cold Agglutinins Test
References in periodicals archive ?
Kit dosage, id-nacl / enzyme, enzymatic test and cold agglutinins in card with 6 microtubes containing gel in saline to reverse grouping of the abo system.
Blood banks employ warm saline washes to remove the circulating antibody that coats the RBCs when cross-matching blood for patients with cold agglutinins.
Causes of Raynaud's phenomenon* ** Anorexia nervosa ** Autoimmune diseases ** Cancer ** Connective tissue disease ** Hematologic causes (cryoglobulinemia, cold agglutinins, macroglobulins, polycythemia) ** Hypothyroidism ** Intraarterial injections ** Neoplasms ** Neurologic disorders ** Obstructive arterial disease ** Predisposing drugs (beta-blockers, ergot alkaloids, sympathomimetics, clonidine, narcotics, cocaine, methysergide, some chemotherapeutic agents, estrogen, and cyclosporine) ** Systemic sclerosis ** Trauma (vibration/electric shock/frostbite/meat cutters) ** Vasculitis and hepatitis B antigenemia ** Vinyl chloride exposure * From Shinn, 2008 (8).
For example, patients with Mycoplasma pneumoniae infections, the presence of cold agglutinins is useful in diagnosis.
Roeth and his colleagues investigated the potential effect of eculizumab therapy in one patient with CAD, a rare and severe disease characterized by the production of circulatory cold agglutinins, a type of monoclonal antibody that lead to hemolysis.
Before the availability of new technologies, cold agglutinins were used to confirm a diagnosis of M.
Abstract: A 40-year-old white male developed Mycoplasma pneumoniae pneumonia (IgM titer 1:256) as well as autoimmune hemolytic anemia due to cold agglutinins (titer of 1:512).
Sputum, blood, and urine cultures; smears for acid-fast bacilli; and tests for Legionella urinary antigen, influenza nasopharyngeal antigen, and cold agglutinins were negative.
3] MCHC Hyperlipidemia, cold agglutinins WBC >50 000/ [mm.
Kit dosage, id-nacl/enzima, enzymatic test and cold agglutinins in card 6 microtubes containing gel in saline to reverse grouping abo system.
For example, low mean corpuscular volume may signify either iron deficiency or a hemoglobinopathy, whereas high MCV may suggest cold agglutinins, vitamin B[sub.