Excision methods include cold knife conization
(CKC), loop electrosurgical excision procedure (LEEP), or laser.
It may be considered as a suitable alternative to cold knife conization
or hysterectomy for younger females who are yet to complete their families.
The physician decided to do a cold knife conization
to rule out a more severe lesion.
A recent meta-analysis of 27 controlled cohort studies found that cold knife conization
and LEEP were associated with increased obstetrical risks, such as delivery at less than 37 weeks' gestation and a birth weight <2500 g (TABLE 2).
Further, the use of neoadjuvant chemotherapy followed by cold knife conization
for fertility preservation in women with larger tumors has been proposed.
A comparison between loop electrosurgical excision procedure and cold knife conization
for treatment of cervical dysplasia: residual disease in a subsequent hysterectomy specimen.
Referral for cold knife conization
was limited to patients with glandular atypia on biopsy or endocervical curretage, or colposcopic impression of glandualr atypia.
One study found microfibrillar collagen (MC) use during cold knife conization
resulted in nonsignificant reduction in operative time and similar hemostatic results compared to Sturmdorf suture (Obstet.
Based on prior studies of pregnant patients who had undergone cold knife conization
, complications do not occur until there is considerably greater cervical tissue excision than that which occurs in clectrosurgical loop excisions.
Today, we have myriad tools to detect and treat cervical cancer, from Pap smears to colposcopies, and from directed biopsy to laser and electrosurgical therapies to cold knife conization
A randomized trial comparing two methods of cold knife conization
with laser surgery.