Cogan syndrome

Also found in: Wikipedia.

oc·u·lo·ves·tib·u·lo·au·di·to·ry syn·drome

a nonsyphilitic interstitial keratitis characterized by an abrupt onset with vertigo and tinnitus followed by hearing impairment; about 50% of patients have an associated systemic disease, most commonly polyarteritis nodosa.
Synonym(s): Cogan syndrome

Cogan syndrome

An autoimmune condition characterized by interstitial keratitis and bilateral, rapidly progressive audiovestibular dysfunction Clinical Vasculitis of CNS, aorta, heart, pericardium, lungs; ocular complaints–photophobia, blurred vision, lacrimation, pain; Meniere's disease-like Sx–vertigo, ataxia vegetative Sx, with progression to complete absence of vestibular function, manifested by ataxia and oscillopsia, bilateral hearing loss Management High dose steroids, immunosuppression

Cogan syndrome

[David G. Cogan, U.S. ophthalmologist, 1908–1993]
Interstitial keratitis associated with tinnitus, vertigo, and usually deafness.


David G., U.S. ophthalmologist, 1908-1993.
Cogan syndrome - a nonsyphilitic interstitial keratitis with vertigo and tinnitus, followed by deafness. Synonym(s): oculovestibulo-auditory syndrome
Cogan-Reese syndrome - syndrome of glaucoma, iris atrophy, decreased corneal endothelium, anterior peripheral synechia, and multiple iris nodules. Synonym(s): iridocorneal endothelial syndrome
References in periodicals archive ?
Cogan syndrome was initially suspected in view of the characteristic interstitial keratitis, fluctuating sensorineural hearing loss, and episodic vertigo.
When a review of the patient's ophthalmologic examination revealed that he suffered from recurrent iritis and not interstitial keratitis or uveitis, the diagnosis of Cogan syndrome was questioned.