cofactor

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cofactor

 [ko´fak-ter]
an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II a member of the serpin group that inhibits thrombin.

co·fac·tor

(kō'fak'ter, tōr),
1. Synonym(s): coenzyme
2. An atom or molecule essential for the action of a large molecule, for example, heme in hemoglobin, magnesium in chlorophyll. Solo metal ions are regarded as cofactors for proteins, but not as coenzymes.

cofactor

/co·fac·tor/ (ko´fak-ter) an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II  a serine proteinase inhibitor of the serpin family that inhibits thrombin.

cofactor

(kō′făk′tər)
n.
1. One of two or more contributing factors.
2. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.

co·fac·tor

(kō'fak'tŏr)
1. Synonym(s): coenzyme.
2. An atom or molecule essential for the action of a large molecule; e.g., heme in hemoglobin, magnesium in chlorophyll.

cofactor

a substance that is essential for the catalytic activity of some enzymes, binding to the enzyme only during the reaction. Cofactors can be metallic ions, or nonprotein organic molecules (coenzymes) such as vitamins in the B-COMPLEX.

co·fac·tor

(kō'fak'tŏr)
An atom or molecule essential for the action of a large molecule.

cofactor

an element or principle, e.g. a coenzyme, with which another must unite in order to function.

ristocetin cofactor
see ristocetin cofactor.
References in periodicals archive ?
This Km concept applies especially to cofactors that function as true substrates of the enzyme in question.
Note that a Darboux polynomial with zero cofactor is a polynomial first integral.
The possible exceptions, histidinal and histinidol, may have resulted from components of a vestigial cofactor pathway.
In our series, HSV-2 DNA is not found integrated to human genome of adenocarcinoma of the uterine cervix, and does not seem to be a cofactor of HPV on the development of this cancer subtype," Dr.
Rubber yield is a function of the availability of substrate and cofactor, the rate of reaction, and the number of reactions occurring at any one time.
At present, it is unclear which other lipid-related cofactors might play a role in apo E 2/2-related hyperlipidemia.
Multiple-QTL models allow statistical control of genetic background noise due to QTL on other portions of the genome that are segregating in the population using multiple regression on marker cofactors (Jansen and Stem 1994; Jannink and Jansen 2001).
Russell and Martin offer yet another piece of circumstantial evidence that life may have emerged from iron sulfide-catalyzed chemistry: Many of the large proteins that drive basic biochemical reactions today--such as ferredoxin, a protein that mediates metabolic reactions--rely on smaller iron sulfur cofactors.
Cofactors for human immunodeficiency virus entry, into primary macrophages.
Confirmation of these results, the author argues, will bring about "wider acceptance that high parity and long-term use of oral contraceptives can act as cofactors in the genesis of cervical cancer.
Despite its universal importance in DNA synthesis, different organisms have evolved diverse enzymatic cofactors to catalyze this reaction.