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Coagulation cascade |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.01 sec. |
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Coagulation cascade The sequence of biochemical activities, involving clotting factors, that stop bleeding by forming a clot. Mentioned in: Fibrin Split Products, Partial Thromboplastin Time |
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| Thus, the coagulation cascade and the fibrinolytic systems are functionally separate. Two of the new proteins thwart clotting by binding to and inactivating factor Xa; the third protein stymies factor VIIa and "inhibits the initiation of the entire coagulation cascade," says Vlasuk. Upon contact with a bleeding surface, the matrix hydrates and the fibrinogen-thrombin reaction initiates the key step in the coagulation cascade. |
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Coagulation cascade
