coagulase(redirected from Coagulase-negative)
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a bacterial enzyme that reacts with a cofactor found in blood plasma to catalyze the formation of fibrin from fibrinogen. It is produced by most of the virulent strains of staphylococci, and by Yersinia pestis.
coagulase/co·ag·u·lase/ (-lās) an antigenic substance of bacterial origin, produced by staphylococci, which may be causally related to thrombus formation.
Any of various enzymes, such as rennin or thrombin, that induce coagulation.
Etymology: L, coagulare, to curdle
an enzyme produced by bacteria, particularly Staphylococcus aureus, that promotes the formation of fibrin from fibrinogen to form thrombi.
coagulaseAn enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin. This ability probably contributes to the tendency of the organism to form abscesses.
an antigenic substance of bacterial origin, produced chiefly by staphylococci, which may be causally related to thrombus formation.
enzymatic conversion of fibrinogen in rabbit plasma to fibrin is used as a means of identifying pathogenic species of staphylococci. The test may be carried out rapidly on a slide or in several hours or overnight in a tube. Most coagulase-positive staphyloccoci are pathogenic; coagulase-negative ones commonly are not.