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co-stimulation |
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co-stimulation
Immunology The delivery of a 2nd signal from an antigen-presenting cell to a T cell, which rescues an activated T cell from anergy, allowing it to produce the lymphokines necessary for production of additional T
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Cambridge, MA) announced they have entered into an agreement in which they will collaborate to research, develop and commercialize new antibody therapeutics generated from two validated Millennium targets: a co-stimulatory molecule and a chemokine receptor. PDA001 cells constitutively express moderate levels of HLA Class I and undetectable levels of HLA Class II, and they do not express the co-stimulatory molecules CD80 and CD86. LFA-3 isa component of TRICOM, Therion's co-stimulatory system for optimizingimmune response against tumor cells. |
Co-stimulatory |
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