cofactor

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cofactor

 [ko´fak-ter]
an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II a member of the serpin group that inhibits thrombin.

co·fac·tor

(kō'fak'ter, tōr),
1. Synonym(s): coenzyme
2. An atom or molecule essential for the action of a large molecule, for example, heme in hemoglobin, magnesium in chlorophyll. Solo metal ions are regarded as cofactors for proteins, but not as coenzymes.

cofactor

/co·fac·tor/ (ko´fak-ter) an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II  a serine proteinase inhibitor of the serpin family that inhibits thrombin.

cofactor

(kō′făk′tər)
n.
1. One of two or more contributing factors.
2. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.

co·fac·tor

(kō'fak'tŏr)
1. Synonym(s): coenzyme.
2. An atom or molecule essential for the action of a large molecule; e.g., heme in hemoglobin, magnesium in chlorophyll.

cofactor

a substance that is essential for the catalytic activity of some enzymes, binding to the enzyme only during the reaction. Cofactors can be metallic ions, or nonprotein organic molecules (coenzymes) such as vitamins in the B-COMPLEX.

co·fac·tor

(kō'fak'tŏr)
An atom or molecule essential for the action of a large molecule.

cofactor

an element or principle, e.g. a coenzyme, with which another must unite in order to function.

ristocetin cofactor
see ristocetin cofactor.
References in periodicals archive ?
And this makes us believe there may be other fusion co-factors that serve the same purpose for other HIV strains.
is the synthetic form of 6R-BH4, a naturally occurring co-factor that works in conjunction with the enzyme phenylalanine hydroxylase (PAH) to metabolize phenylalanine into tyrosine.
Selenium: A vital co-factor for glutathione, the body's premier antioxidant, selenium also confers protection against infections.
Having concluded from this early work that upstream microvascular pressure might be an important co-factor in the development of VILI, we next addressed the question of how the number of ventilatory cycles occurring over a timed interval influences the rate of edema formation or severity of histological alterations when maximum, minimum, and mean airway pressures are held identical.
Al Saeed also stressed that half of all H1N1 fatalities in Oman, so far, had had co-factor diseases.
1) Coenzyme Q10 is an essential mitochondrial co-factor and natural antioxidant; its synthesis in the body is blocked by the statin drugs widely prescribed to reduce cholesterol levels.
They are also an excellent source of the trace mineral manganese, an essential co-factor in energy production and in our antioxidant defence.
While HIV/AIDS is predominantly spreading through sexual intercourse, this biological co-factor induced by malaria has contributed considerably to the spread of HIV by increasing HIV transmission probability per sexual act," said Abu-Raddad, an HIV/AIDS research scientist in the Hutchinson Center's Statistical Center for HIV/AIDS Research and Prevention and the Center for Studies in Demography and Ecology at the University of Washington.
When the co-factor epithiospecifier protein (ESP) is present, an inactive hydrolysis product--sulforaphane nitrile (SFN)--forms at the expense of SF.
In addition, mouse studies have already resulted in some discoveries about HIV, including the identification of co-receptors, cyclin T1 (a necessary co-factor for Tat and TAR during transcriptional elongation), and host factors required for viral assembly and release.
Vitamin B12 is a required co-factor for this enzyme but for some reason in the so-called vitamin B12-responsive forms of MMA there is insufficient co-factor available to the enzyme.